Get medical attention immediately if symptoms occur. Phenylalanine ammonialyase an overview sciencedirect topics. The occupational safety and health administrations osha hazard communication standard 29 cfr 1910. Identification of the substancemixture and of the companyundertaking 1. It is not known what exactly to expect with a phenylalanine overdose, although the effects will likely vary, depending on the phenylalanine dosage, as well as on other factors. If inhaled if breathed in, move person into fresh air. Nacetyll phenylalanine is the nacetyl derivative of l phenylalanine. Product identifier product name 3,4dihydroxydlphenylalanine product number fd58239 synonyms. Structure, properties, spectra, suppliers and links for. Calcium dichloride, calcium chloride, calcium chloride pellets product use. Material safety data sheet page 1 of 2 dlphenylalanine. Most important symptomseffectsnone reasonably foreseeable. Lphenylalanine may be helpful in some with depression.
On the mechanism of inhibition of intestinal alkaline phosphatase by lphenylalanine i. Accidental release measures contain spill and collect, as appropriate. Kapalka, in nutritional and herbal therapies for children and adolescents, 2010. Safety data sheet according to 29cfr19101200 and ghs rev. Product identifier product name 4nitrol phenylalanine product number fn46969. Sigmaaldrich p2126 page 2 of 6 if inhaled if breathed in, move person into fresh air. This product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all of the information required by those regulations. P280 wear protective gloves protective clothing eye protection face protection.
Msds contains all of the information required by those regulations. Although it is a natural product, phenylalanine safety issues still need to be kept in mind especially for people taking it in supplement form. Identification of a plastidial phenylalanine exporter that. The information provided on this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. It is found in many foods and in some dietary supplements. Fishman from the department of pathology oncology, tufts university school 0 medicine and the cancer research. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. L phenylalanine revision date 10feb2015 x listed e indicates a substance that is the subject of a section 5e consent order under tsca. Safety data sheets sdss environmental health and safety.
Firstaid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening. Material safety data sheet lphenylalanine 1 chemical product and company identification msds name. Also ask for the brand name of the pesticide, a material safety data sheet. The aromatic amino acid lphenylalanine is a vital constituent of proteins in all living organisms and serves as a versatile precursor for thousands of indispensable metabolites1. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Through this pathway of conversion, important neurotransmitters and hormones are synthesized such as ldopa, dopamine, epinephrine, norepinephrine, thyroxine, and melanin. Cuweblogin is a component of cornell universitys central authentication service. Use the product attributes below to configure the comparison table. The antidepressant effect of dl phenylalanine may be accounted for by its precursor role in the synthesis of the neurotransmitters norepinephrine and dopamine. These sdss are designed to provide essential information. Buy 4nitrolphenylalanine cas 949995, a product for proteomics research, from santa cruz. Find msds or sds, a coa, data sheets and more information.
Phenylalanine is an essential amino acid which can be converted into other amino acids, most notably tyrosine. Phenylalanine ammonialyase is an important plant enzyme that eliminates ammonia from phenylalanine to form transcinnamic acid, a precursor of lignins, flavanoids, and coumarins. Dr brennanolsen and her team are committed to investigating msds. Safety precautions also include making sure that the. Product identifier product name 4nitrolphenylalanine product number fn46969. Show this safety data sheet to the doctor in attendance.
Sds of lphenylalanyllphenylalanine, safety data sheets. F indicates a substance that is the subject of a section 5f rule under tsca. An overview phenylalanine is an amino acid essential for human nutrition. Safety data sheet a university in missouri, college in. In addition to chemwatch, the cornell libraries web site provides access to brethricks handbook of reactive chemical hazards from 2007, which is. Phenylalanine, usp is an amino acid, a building block of protein. Sphenylalanine msds material safety data sheet or sds, coa and coq, dossiers. For example, if you have certain medical conditions, you may need to closely watch your intake of phenylalanine. Safety of phenylalanine although it is a natural product, phenylalanine safety issues still need to be kept in mind especially for people taking it in supplement form. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Material safety data sheet section 1 hippuryllphenylalanine 1 chemical product and company identification msds name. Ingestion never give anything by mouth to an unconscious person.
The information contained herein is applicable solely to the chemical substance when used as a usp reference standard and does not necessarily relate to any other use of the substance. Ingold, structure and mechanism in organic chemistry, cornell university press, ithaca. The primary use of d phenylalanine as a health supplement is the relief of discomfort. Dlphenylalanine is a racemic mixture of phenylalanine, an aromatic amino acid with antidepressant, analgesic and appetite suppressant properties. Physical and chemical properties molecular formula c9h11no2. Precautionary statements p261 avoid breathing dust. Wear suitable protective equipment during handling. Material safety data sheet l phenylalanine 1 chemical product and company identification msds name. It may also be useful in the treatment of vitiligo.
It is a nacyll phenylalanine, a nacetyllamino acid and a nacetylphenylalanine. Product and company identification dl phenylalanine. Secondary inhalation exposures could occur when cleaning equipment, or. Download msds pdf search msds currently available for download bioworld offers lphenylalanine for your research at low price. In case of skin contact wash off with soap and plenty of water. Follow the specific cleanup procedures on the chemicals msds. All spectrum chemical usp products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Dl phenylalanine is a racemic mixture of phenylalanine, an aromatic amino acid with antidepressant, analgesic and appetite suppressant properties. On the mechanism of inhibition of intestinal alkaline. Always check your browsers address bar before you enter your netid password to make sure the address starts with where web is either web1, web2, web3 or web4. The information contained herein is applicable solely to the chemical substance when used as a usp reference standard and does. Pah encodes the enzyme phenylalanine hydroxylase that is the ratelimiting step in phenylalanine catabolism.
Tandem mass spectrometry data independently generated by scripps center for metabolomics is available to view or download in pdf. Commission regulation eu no 2015830 of 28 may 2015. Sigmaaldrich material safety data sheet product name d. View product specific information, msds, references and. Always check your browsers address bar before you enter your netid password to make sure the address starts with cornell. Sigmaaldrich material safety data sheet date printed.
Phenylalanine is an amino acid found in mothers milk and a number of foods, including meat, poultry, fish, cottage cheese, lentils. Material safety data sheet usp reference standards are sold for chemical test and assay purposes only, and not for human consumption. This essential amino acid is classified as neutral, and nonpolar because of the inert and hydrophobic nature of the benzyl side chain. L2amino3phenylpropionic acid company identification. Lphenylalanine revision date 10feb2015 inhalation move to fresh air.
Elevated brain norepinephrine and dopamine levels are thought to be associated with. Ingestion clean mouth with water and drink afterwards plenty of water. If you are unsure of the authenticity of any online university. Sigmaaldrich material safety data sheet product name dl. L phenylalanine methyl ester hydrochloride revision date 18jan2018 component casno weight % methyl lphenylalaninate hydrochloride 7524507 95 4. Lphenylalanine reagentgrade,98% 63912 sigmaaldrich. Since the activity deteri orated even at 0, dialysis was carried out for no longer than 3 hours with. Kinetic studies received for publication, july 21, 1965 ntinai k. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. This chemicals molecular formula is c 12 h 16 n 2 o 3 and molecular weight is. In case of eye contact flush eyes with water as a precaution. The phenylalanine, alanyl, with the cas registry number 1999457, is also known as 22aminopropanoylamino3phenylpropanoic acid. Cornell ehs provides campus wide access to chemwatch, an online safety data sheet sds database consisting of over 250,000 chemwatch authored documents, and million vendor supplied documents.
Scientists at cornell university are conducting research funded by. View product specific information, msds, references and buying faq. Sigma a59 page 5 of 6 inhalation may be harmful if inhaled. It is a nacyllphenylalanine, a nacetyllamino acid and a nacetylphenylalanine.
In humans, phenylalanine is an essential amino acid obtained through the diet primarily from plantbased sources, either directly or indirectly. Phenylalanine is an essential amino acid meaning that it cannot be made in the body and must be ingested in the diet. Signs and symptoms of exposure to the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Sigmaaldrich material safety data sheet product name.
S phenylalanine msds material safety data sheet or sds, coa and coq, dossiers. Safety data sheet 4nitrolphenylalanine according to regulation ec no 19072006, annex ii, as amended. Phenylalanine, l 63912 potassium gluconate phenylethyl2 acetate 103457 phosphalase, acid 9001778 phosphate buffered saline pbs potassium iodide phosphatidyl choline, lalpha potassium phosphate, dibasic, anhydrous8002435. There is some evidence that lphenylalanine may exacerbate tardive dyskinesia in some schizophrenic patients and in some who have used neuroleptic drugs. Nacetyllphenylalanine is the nacetyl derivative of lphenylalanine. Histidine ammonialyase catalyzes the first step in histidine degradation.
Material safety data sheet msds for l phenylalanine section 4 first aid measures eyes rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Our msds database is an easy to use, do it yourself tool, and best of all. The primary use of dphenylalanine as a health supplement is the relief of discomfort. Undecylenoyl phenylalanine is a compound that includes amino acids and lipid residue, used in cosmetics and personal care products, specifically whitening formulas, to prevent skin cells from producing melanin pigmentation. Safety data sheet 4nitrol phenylalanine according to regulation ec no 19072006, annex ii, as amended.
It belongs to the product categories of biochemistry. Safety data sheet northwest missouri state university. The antidepressant effect of dlphenylalanine may be accounted for by its precursor role in the synthesis of the neurotransmitters norepinephrine and dopamine. Phenylalanine ammonialyase an overview sciencedirect. It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine. Training the workers on the potential health hazards associated with product vapor, dust or fume is important.
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